Useful books

Ellis, AM, Mayhew, CA. Proton transfer reaction mass spectrometry: principles and applications. Wiley, 2014. ISBN: 978-1-4051-7668-2.

Eiceman, GA, Karpas, Z, Hill, HH. Ion mobility spectrometry. 3rd ed. CRC Press, 2013. ISBN: 13: 978-1439859971.

Warneck P, Williams, J. The atmospheric chemist’s companion. Springer, 2012. ISBN-10: 9400722745, ISBN-13: 978-9400722743.

Partners’ relevant publications prior to IMPACT


  1. Kalogridis, C, Gros, V, Sarda-Estève, R, Langford, B, Loubet, B, Bonsang, B, Bonnaire, N, Nemitz, E, Genard, A-C, Boissard, C, Fernandez, C, Ormeño, E, Baisnee, D, Reiter I, J. Lathière. Concentrations and fluxes of isoprene and oxygenated VOCs at a French Mediterranean oak forest. Atmos. Chem. Phys., 14 (2014): 10085–10102.
  2. Genard-Zielinski, AC, Boissard, C, Fernandez, C, Kalogridis, J. Lathière, J, Gros, V, Orts, J-P, Bonnaire, N, Ormeño, E. Variability of BVOC emissions from a Mediterranean mixed forest with a focus on Quercus pubescens at the O3HP. Atmos. Chem. Phys. Disc., (2014): 17225–17261.
  3. Dolgorouky, C, Gros, V., Sarda-Esteve, R, Sinha, V, Williams, J, Marchand, N, Sauvage, S, Poulain, L, Sciare, J, Bonsang, B. Total OH reactivity measurements in Paris during the 2010 MEGAPOLI winter campaign. Atmos. Chem. Phys., 12 (2012): 9593–9612.
  4. Gros, V, Gaimoz, C, Herrmann, F, Custer, T, Williams, J, Bonsang, B, Sauvage, S, Locoge, N, d’Argouges, O, Sarda-Estève, R, Sciare, J. Volatile organic compounds sources in Paris in spring 2007. Part I: Qualitative analysis. Environmental Chemistry, 8 (2011): 74–90.
  5. Gaimoz, C, Sauvage, S, Gros, V, Herrmann, F, Williams, J, Locoge, N, Bonsang, N, d’Argouges, O, Sarda-Estève, R, Sciare, J. Volatile organic compounds sources in Paris in spring 2007. Part II: Source apportionment. Environmental Chemistry, 8 (2011): 91–103.


  1. Sabo, M, Matejčík, Š. Ion mobility spectrometry for monitoring high-purity oxygen. Anal. Chem., 83 (2011): 1985–1989.
  2. Sabo, M, Matejčík, Š. Corona discharge ion mobility spectrometry with orthogonal acceleration time of flight mass spectrometry for monitoring of volatile organic compounds. Anal. Chem., 84 (2012): 5327–5334.
  3. Sabo, M, Okuyama, Y, Kučera, M, Matejčík, Š. Transport and stability of negative ions generated by negative corona discharge in air studied using ion mobility-oaTOF spectrometry. Int. J. Mass Spectrom., 334 (2013): 19–26.
  4. Sabo M, Matejčík, Š. A corona discharge atmospheric pressure chemical ionization source with selective NO+ formation and its application for monoaromatic VOC detection. Analyst, 138 (2013): 6907–6912.
  5. Sabo M, Malásková, M, Matejčík, Š. Laser desorption with corona discharge ion mobility spectrometry for direct surface detection of explosives. Analyst, 139 (2014): 5112–5117.
  6. Han, HY, Wang, HM, Jiang, HH, Stano, M, Sabo, M, Matejčík, Š, Chu, YN. Corona discharge ion mobility spectrometry of ten alcohols. Chinese Journal of Chemical Physics, 22 (2009): 605.
  7. Sabo, M, Páleník, J, Kučera, M, Han, H, Wang, H, Chu, Y, Matejčík, Š. Atmospheric pressure corona discharge ionisation and ion mobility spectrometry/mass spectrometry study of the negative corona discharge in high purity oxygen and oxygen/nitrogen mixtures. Int. J. Mass Spect., 293(2010): 23–27.
  8. Sabo, M, Matuska, J, Matejčík, Š.Specific O2-generation in corona discharge for ion mobility spectrometry, Talanta 85 (2011): 400–405.
  9. Feng, H, Niu, W, Han, H, Huang, C, Wang, H, Matuska, J, Sabo, M, Matejčík, Š, Jiang, H, Chu, Y. Rate constants of electron attachment to chlorobenzenes measured by atmospheric pressure nitrogen corona discharge electron attachment ion mobility spectrometry, Int. J. Mass Spect., 305 (2011):30–34.
  10. Okuyama, Y, Sabo, M, Itoh, H, Matejčík, Š. Formations of negative ions in SF6/N2 mixtures and their transport at atmospheric pressure. Eur. Phys. J. Appl. Phys., 61 (2013): 24320, doi: 10.1051/epjap/2012120448.
  11. Sabo, M, Lichvanova, J. Orszagh, J, Mason, N, Matejčík, Š. Experimental simulation of negative ion chemistry in Martian atmosphere using ion mobility spectrometry-mass spectrometry, Eur. J. Phys. D., 68 (2014) Art. Nr. 216, doi: 10.1140/epjd/e2014-40836-9.
  12. Sabo, M, Malásková, M, Matejčík, Š. Ion mobility spectrometry-mass spectrometry studies of ion processes in air at atmospheric pressure and their application to thermal desorption of 2,4,6-trinitrotoluene, Plasma Sources Sci.&Technol., 23 (2014): Art. Nr. 015025, doi: 10.1088/0963-0252/23/1/015025.
  13. Sabo, M, Malásková, M, Matejčík, Š. Laser desorption with corona discharge ion mobility spectrometry for direct surface detection of explosives. Analyst, 139 (2014): 5112, doi: 10.1039/c4an00621f.
  14. Sabo, M, Malásková, M, Harmathova, O, Hradski, J, Masar, M, Radjenovic, B, Matejčík, Š. Analytical Chemisty, 87 (2015) 7389–7394, doi: 10.1021/acs.analchem.5b01585. Published: Jul 21 2015.


  1. Sovova, K, Shestivska, V, Spanel, P. Real-time quantification of traces of biogenic volatile selenium compounds in humid air by selected ion flow tube mass spectrometry. Analytical Chemistry, 2012, 84(11): 4979–4983.
  2. Spanel, P, Smith, D. Progress in SIFT-MS: breath analysis and other applications. Mass Spectrometry Reviews, 2011, 30(2): 236–267.
  3. Olivares, A, Dryahina, K, Luis Navarro, J, Flores, M, Smith, D, Spanel, P. Selected ion flow tube-mass spectrometry for absolute quantification of aroma compounds in the headspace of dry fermented sausages. Analytical Chemistry, 2010, 82(13): 5819–5829.
  4. Amann, A, Spanel, P, Smith, D. Breath analysis: the approach towards clinical applications. Mini reviews in medicinal chemistry, 2007, 7(2): 115–129.
  5. Smith, D, Spanel, P, Selected ion flow tube mass spectrometry (SIFT-MS): for on-line trace gas analysis. Mass Spectrometry Reviews, 2005, 24(5): 661–700.


  1. Romano, A, Fischer, F, Herbig, J, Campbell-Sills, H, Coulon, J, Lucas, P, Cappellin, L, Biasioli, F. Wine analysis by FastGC proton-transfer reaction-time-of-flight-mass spectrometry. International Journal of Mass Spectrometry, 369 (2014): 81–86.
  2. Materić, D, Lanza, M, Sulzer, P, Herbig, J, Bruhn, D, Turner, C, Mason, N, Gauci, V, Monoterpene separation by coupling proton transfer reaction time-of-flight mass spectrometry with fastGC. Anal. Bioanal. Chem., doi: 10.1007/s00216-015-8942-5.
  3. Sulzer, P, Hartungen, E, Hanel, G, Feil, S, Winkler, K, Mutschlechner, P, Haidacher, S, Schottkowsky, R, Gunsch, D, Seehauser, H, Striednig, M, Jürschik, S, Breiev, K, Lanz, M, Herbig, J, Märk, L, Märk, TD, Jordan, A. A proton transfer reaction-quadrupole interface time-of-flight mass spectrometer (PTR-QiTOF): high speed due to extreme sensitivity. International Journal of Mass Spectrometry, 368 (2014): 1–5.


  1. Nölscher, AC, Butler, T, Auld, J, Veres, P, Munoz, A, Taraborrelli, D, Vereecken, L, Lelieveld, J, Williams, J. Using total OH reactivity to assess isoprene photooxidation via measurement and model. Atmospheric Environment, 89 (2014): 453–463.
  2. Veres, P, Behrendt, T, Klapthor, A, Meixner, FX, Williams, J. Volatile organic compound emissions from soil: using proton-transfer-reaction time-of-flight mass spectrometry (PTR-TOF-MS): for the real time observation of microbial processes. Biogeosciences Discuss., 11 (2014): 12009–12038.
  3. Veres, PR, Faber, P, Drewnick, F, Lelieveld, J, Williams, J. Volatile organic compound measurements during a football match: assessing human emissions in the atmosphere. Atmospheric Environment, 77 (2013):1052–1059. doi: 10.1016/j.atmosenv.2013.05.076.
  4. Nölscher, AC, Williams, J, Sinha, V, Custer, T, Song, W, Johnson, AM, Axinte, R, Bozem, H, Fischer, H, Pouvesle, N, Phillips, G, Crowley, JN, Rantala, P, Rinne, J, Kulmala, M, Gonzales, D, Valverde-Canossa, J, Vogel, A, Hoffmann, T, Ouwersloot, HG, Vilà-Guerau de Arellano, J, Lelieveld, J. Summertime total OH reactivity measurements from boreal forest during HUMPPA-COPEC 2010 Atmos. Chem. Phys., 12 (2012): 8257–8270.
  5. Warneck P, Williams, J. The atmospheric chemist’s companion. Springer, 2012. ISBN-10: 9400722745, ISBN-13: 978-9400722743.


  1. Cristescu, SM, Kiss, R, te Lintel Hekkert, S, Dalby, M, Harren, FJM, Risby, TH, Marczin, N. Real-time monitoring of endogenous lipid peroxidation by exhaled ethylene in patients undergoing cardiac surgery. American Journal of Physiology – Lung Cellular and Molecular Physiology, 307 (7) (2014): L509–L515. doi: 10.1152/ajplung.00168.
  2. Samudrala, D, Lammers, G, Mandon, J, Blanchet, L, Schreuder, THA, Hopman, MT, Harren, FJM, Tappy, L, Cristescu, SM. Breath acetone to monitor life style interventions in field conditions: an exploratory study. Obesity, 22 (2014): 980–983.
  3. tenOever, J, Mandon, J, Netea, MG, van Deuren, M, Harren, FJM, Cristescu, SM, Pickkers, P. Pulmonary infection, and not systemic inflammation, accounts for increased concentrations of exhaled nitric oxide in patients with septic shock. J. Breath Res., 7 (2013): 036003, doi:10.1088/1752-7155/7/3/036003
  4. Arslanov, D, Castro, MPP, Creemers, NA, Neerincx, AH, Spunei, M, Mandon, J, Cristescu, SM, Merkus, P, Harren, FJM. Optical parametric oscillator based photoacoustic detection of hydrogen cyanide for bio-medical applications. J. Biomedical Optics, 18 (2013): 107002-1-8.
  5. Cristescu, SM, Mandon, J, Harren, FJM, Merilainen P, Hogman, M. Methods of NO detection in exhaled breath. J. Breath Res., 7 (2013): 017104.


  1. de Lacy Costello, B, Amann, A, Al-Kateb, H, Flynn, C, Filipiak, W, Khalid, T, Osborne, D, Ratcliffe, NM. A review of the volatiles from the healthy human body. J Breath Res., 8 (2014): 014001.
  2. Filipiak, W, Filipiak, A, Sponring, A, Schmid, T, Zelger, B, Ager, C, Klodzinska, E, Denz, H, Jamnig, H, Pizzini, A, Troppmair, J, Amann, A. Comparative analyses of volatile organic compounds (VOCs): from patients, tumors and transformed cell lines for the validation of lung cancer-derived breath markers. J Breath Res., 8 (2014): 027111.
  3. Haick, H, Broza, YY, Mochalski, P, Ruzsanyi, V, Amann, A. Assessment, origin, and implementation of breath volatile cancer markers Chem. Soc. Rev., 43 (2014): 1423–49.
  4. Bajtarevic, A, Ager, C, Pienz, M, Klieber, M, Schwarz, K, Ligor, M, Ligor, T, Filipiak, W, Denz, H, Fiegl, M, Hilbe, W, Weiss, W, Lukas, P, Jamnig, H, Hackl, M, Haidenberger, A, Buszewski, B, Miekisch, W, Schubert J, Amann, A. Noninvasive detection of lung cancer by analysis of exhaled breath. BMC Cancer, 9 (2009): 348.
  5. Filipiak, W, Sponring, A, Filipiak, A, Ager, C, Schubert, J, Miekisch, W, Amann A, Troppmair, J. TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro. Cancer epidemiology, biomarkers & prevention, 19 (2010): 182–95.


  1. Miekisch, W, Hengstenberg, A, Kischkel, S, Beckmann, U, Mieth, M, Schubert, JK. Construction and evaluation of a versatile CO2 controlled breath collection device. IEEE Sensors Journal, 10 (2010): 211–215.
  2. Schubert, R, Schwoebel, H, Mau-Moeller, A, Behrens, M, Fuchs, P, Sklorz, M, Schubert, JK, Bruhn, S, Miekisch, W. Metabolic monitoring and assessment of anaerobic threshold by means of breath biomarkers. Metabolomics, 8 (2012): 1069–1080.
  3. Trefz, P, Koehler, H, Klepik, K, Moebius, P, Schubert, J, Reinhold, P, Miekisch, W. Volatile emissions from Mycobacterium avium subsp. paratuberculosis mirror bacterial growth and enable distinction of different strains. PLoS One, (2013): 8(10):e76868. doi: 10.1371/journal.pone.0076868.
  4. Trefz, P, Schmidt, M, Oertel, P, Obermeier, J, Brock, B, Kamysek, S, Dunkl, J, Schubert, JK, Miekisch, W. Continuous real time breath gas monitoring in the clinical environment by proton-transfer-reaction-time of flight-mass spectrometry. Anal. Chem., 85 (2013): 10321.
  5. Sukul, P, Trefz, P, Schubert, JK, Miekisch, W. Immediate effects of breath holding manoeuvres onto composition of exhaled breath. J Breath Res. 8(3) (2014): 037102. doi: 10.1088/1752-7155/8/3/037102. Epub 2014 Sep 4.


  1. Mayhew, CA, Sulzer, P, Petersson, F, Haidacher, S, Jordan, A, Märk, L, Watts, P, Märk, TD. Applications of proton transfer reaction time-of-flight mass spectrometry for the sensitive and rapid real-time detection of solid high explosives. Int. J. Mass Spectrom., 289 (2010): 58–63.
  2. Jürschik, S, Sulzer, P, Petersson, F, Mayhew, CA, Jordan, A, Agarwal, B, Haidacher, S, Seehauser, H, Becker, K, Märk, TD. Proton transfer reaction mass spectrometry for the sensitive and rapid real-time detection of solid high explosives in air and water. Anal. Bioanal. Chem., 398 (2010): 2813–2820.
  3. Brown, P, Watts, P, Märk, TD, Mayhew, CA. Proton transfer reaction mass spectrometry investigations on the effects of reduced electric field and reagent ion internal energy on product ion branching ratios for a series of saturated alcohols. Int. J. Mass Spectrom., 294 (2010): 103–111.
  4. Sulzer, P, Petersson, F, Agarwal, B, Becker, KH, Jürschik, S, Märk, TD, Perry, D, Watts, P, Mayhew, CA. Proton transfer reaction mass spectrometry and the unambiguous real-time detection of 2,4,6 TNT. Analytical Chemistry, 84 (2012): 4161–4166.
  5. Kassebacher, T, Sulzer, P, Jürschik, S, Hartungen, E, Jordan, A, Edtbauer, A, Feil, S, Hanel, G, Jaksch, S, Märk, L, Mayhew, CA, Märk, TD. Investigations of chemical warfare agents and toxic industrial compounds with proton-transfer-reaction mass spectrometry (PTR-MS): for a real-time threat monitoring scenario. Rapid Communications in Mass Spectrometry, 27 (2013): 325–332.
  6. Lanza, M, Acton, WJ, Jürschik, S, Sulzer, P, Breiev, K, Jordan, A, Hartungen, E, Hanel, G, Märk, L, Mayhew, CA, Märk, TD. Distinguishing two isomeric mephedrone substitutes with selective reagent ionisation mass spectrometry (SRI-MS):. Journal of Mass Spectrometry, 48 (2013): 1015.
  7. Sulzer, P, Märk, L, Lanza, M, Jürschik, S, Agarwal, B, Märk, TD, González, R, Watts, P, Mayhew, CA. Applications of switching reagent ions in proton transfer reaction mass spectrometric instruments for the improved selectivity of explosive compounds. International Journal of Mass Spectrometry, 354 (2013): 123.
  8. González-Méndez, R, Reich, DF, Mullock, SJ, Corlett, CA, Mayhew, CA. Development and use of a thermal desorption unit and proton transfer reaction mass spectrometry for trace explosive detection: determination of the limits of detection and an investigation of memory effects. International Journal of Mass Spectrom., 385 (2015): 13–18.
  9. Fernández del Río, R, O’Hara, ME, Holt, A, Pemberton, P, Shah, T, Whitehouse, T, Mayhew, CA. Volatile biomarkers in breath associated with liver cirrhosis: comparisons of pre- and post-liver transplant breath samples. EBioMedicine, In press, corrected proof (2015):.

IMPACT’S Publications

  1. Ramón González-Méndez, Peter Watts, David Olivenza-León, D. Fraser Reich, Stephen J. Mullock,
    Clive A. Corlett, Stuart Cairns, Peter Hickey, Matthew Brookes, and Chris A. Mayhew.
    “ Enhancement of compound selectivity using a radio frequency ion-funnel proton transfer reaction mass spectrometer: improved specificity for explosive compounds” Analytical Chemistry 88 (2016) 10624-10630.

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Conferences and meetings


First International Conference on Soft Chemical Ionisation Mass Spectrometry and Applications to Trace Gas Analysis, Dornbirn, Austria 18th-20th September 2017

Outside of the Network


Spectrometry for Security Applications – one-day RSC and IoP workshop 17th December 2015, Physics, University of Birmingham


XXth Symposium on Atomic, Cluster and Surface Physics Sunstar Parkhotel Davos, CH-7270 Davos Platz, Switzerland
7th to 12th February

7th International PTR-MS Conference. University Centre Obergurgl, Tirol, Austria
14th to 19th February

International Society of Ion Mobility Spectrometry Conference, Boston, USA
24th to 28th July 2016

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Useful links



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